منابع مشابه
3D-QSAR and Molecular Docking Studies on the TcPMCA1-Mediated Detoxification of Scopoletin and Coumarin Derivatives
The carmine spider mite, Tetranychus cinnabarinus (Boisduval), is an economically important agricultural pest that is difficult to prevent and control. Scopoletin is a botanical coumarin derivative that targets Ca2+-ATPase to exert a strong acaricidal effect on carmine spider mites. In this study, the full-length cDNA sequence of a plasma membrane Ca2+-ATPase 1 gene (TcPMCA1) was cloned. The se...
متن کاملStudies on Pure Red Cell Aplasia . XI
Thirty-seven patients with pure red cell aplasia (PRCA) were seen between 1 966 and 1 982. Ten patients had accompanying diseases described in association with PRCA, while the remainder had primary PACA. All but two patients were treated with some form of immune manipulation. including corticosteroids. cytotoxic drugs. antithymocyte globulin. splenectomy. thymectomy. and plasmapheresis. Twenty-...
متن کاملElectrochemical Synthesis of Heterocyclic Compounds. XI. Annelation of Coumarin Ring via Cathodic Reduction of 3-Nitrocoumarin Derivatives
Annelation of the coumarin ring was performed via cathodic reduction of 3-nitrocoumarin derivatives (1-4) by controlled potential. The reduction of 3-nitro-4-aminocoumarin, 1, gave 3,4-diaminocoumaDin, 5, and subsequent treatment with formic acid furnished tlie novel 4H [1] benzopyrano [3,4-b] imidazole-4-on ring system 6. The condensation of 5 with trifluoracetic acid anhydride, acetic acid an...
متن کاملThe Antioxidant Activity of New Coumarin Derivatives
The antioxidant activity of two synthesized coumarins namely, N-(4,7-dioxo-2- phenyl-1,3-oxazepin-3(2H,4H,7H)-yl)-2-(2-oxo-2H-chromen-4-yloxy)acetamide 5 and N-(4-oxo-2-phenylthiazolidin-3-yl)-2-(2-oxo-2H-chromen-4-yloxy)acetamide 6 were studied with the DPPH, hydrogen peroxide and nitric oxide radical methods and compared with the known antioxidant ascorbic acid. Compounds 5 and 6 were synthes...
متن کامل[New coumarin derivatives with expected biological activity].
A number of novel 3-bromo-4-methyl-7-methoxy-8-amino substituted coumarins and 2-substituted 7-bromo-6-methyl-8H-pyrano-benzimidazoles, benzoxazoles and/or benzoxazine-8-ones were synthesized for the purpose of pharmacological evaluation. Some representative compounds showed antitumor activity in vitro on Ehrlich ascites carcinoma in the preliminary testing.
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1957
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.77.5_523